PEPID

What's New in PEPID 16.1

 

The latest update is now available for:

Update Now

 

PEPID Emergency Medicine Suite

Special Updates:

  • Powdered Alcohol (Palcohol)

    In March 2015, the Alcohol and Tobacco Tax and Trade Bureau (TTB) had approved for sale and distribution in the USA of several powdered alcohol products. Powdered alcohol is ethanol (drinking alcohol) which has been absorbed into a carbohydrate medium (e.g., dextrin) in order to maintain a dry powder or crystalline form. As of August 2015, 22 states have banned powdered alcohol, 20 states statutorily prohibit the sale of powdered alcohol, two states have temporary one-year statutory bans, and four states regulate it under their existing alcohol statutes.

  • Pregnancy Categories

    The U.S. Food and Drug Administration's (FDA) final rule regarding labeling requirements for pregnancy and lactation became effective on June 30, 2015. As a result, the following changes will apply to PEPID Drug content:

    • “Pregnancy Categories” will be phased out of the content.
    • A new section titled “Pregnancy and Lactation” will contain pertinent data regarding pregnancy, lactation and reproductive risk that will fall in line with the new labeling requirements.
    • New products approved will show this change immediately, as well as products recently approved that are conforming to this change preemptively.
    • Pre-existing products will be updated as the data becomes available.

For more information, visit the FDA website.

Medical Content
  • Cardiology
    • Abdominal Aortic Aneurysm
      • Background/Pathophysiology/Diagnostics
      • Treatment/Complications/Disposition
    • Atrial Flutter
    • Heart Failure
      • Background
      • Pathophysiology
      • Diagnostics
      • Acute Heart Failure Treatment
      • Chronic Heart Failure Treatment: ACCF/AHA Recommendations
      • Prevention and Screening
      • Prognosis
    • Myocardial Rupture
    • Valvular Disorders
      • Aortic Stenosis
      • Tricuspid Stenosis
    • Variant Angina (Prinzmetal Angina)
  • Endocrinology:
    • Hypoaldosteronism
    • Electrolyte Disorders
      • Hypernatremia
      • Hypercalcemia
      • Hyperphosphatemia
      • Hypophosphatemia
    • Respiratory Alkalosis
  • Gastroenterology
    • Boerhaave Syndrome
    • Zollinger-Ellison Syndrome
  • Hematology
    • Anemia: Iron Studies
  • Immunology
    • Systemic Lupus Erythematosus
  • Infectious Diseases
    • Acute Viral Hepatitis: Overview
    • CDC Patient Isolation Guidelines
      • Universal Precautions
      • Categorical Precautions
        • General Information
        • Airborne Precautions
        • Droplet Precautions
        • Contact Precautions
    • Lyme Disease
    • Travel: Fever Work-Up
    • West Nile Virus
  • Medicolegal
    • Elder Abuse
  • Obstetrics and Gynecology
    • Dysfunctional Uterine Bleeding
    • Ectopic Pregnancy
      • Overview
      • Treatment/Disposition
    • Second Half Pregnancy Bleeding
    • Vaginal Bleeding: Diagnostics and Treatment Goals
  • Oncology
    • Basal Cell Carcinoma
    • Hypercalcemia of Malignancy
  • Orthopedics
    • Femoral Neck Fractures
    • Cervical Spine X-Rays
      • Anteroposterior and Odontoid Views
      • Lateral Views
      • Oblique Views (Laminar Views)
  • Pain Management
    • Pain Management in High-Risk Patients: IV Drug Addicts (IVDA)
  • Procedures
    • Mechanical Ventilation
      • Ventilator Management: Overview
      • Ventilator Management: Settings
      • Ventilator Management: Manipulations
      • Ventilator Management: Troubleshooting
    • Thoracentesis Procedure
  • Psychiatry
    • Suicide Risk Assessment
  • Trauma
    • Advance Trauma Life Support (ATLS)
      • Trauma Basics (ABCDEs): Resuscitation Overview
      • Primary Survey
        • Overview
        • Airway and C-Spine
        • Breathing
        • Circulation
        • Control Bleeding
        • Disability
        • Exposure and Environment
      • Secondary Survey
        • Overview
        • Head and Neck
        • Chest
        • Abdomen and Pelvis
        • Extremities
    • Burns
      • Overview
      • Treatment of Minor to Moderate Burns
      • Treatment of Major Burns
      • Inhalation Injury
    • Compartment Syndrome
    • Massive Hemothorax
    • Neck Trauma
      • Background/Pathophysiology
      • Differential Diagnosis
      • Treatment Overview
      • Penetrating Neck Trauma
    • Tension Pneumothorax
    • Transplant Management
      • Overview
      • Post-Transplantation: Infection Differential
  • Toxicology
    • Ethanol (EtOH) Toxicity
    • Sympathomimetics/CNS Stimulants
    • Methanol Poisoning
  • Urology
    • Interstitial Cystitis
  • Wilderness Medicine
    • Acute Mountain Sickness (Altitude Sickness)
    • Frostbite
Drug Knowledgebase
  • 22 drugs added:
    • Atazanavir/Cobicistat
    • Ceftazidime/Avibactam
    • Cholic Acid
    • Darunavir/Cobicistat
    • Diclofenac IV
    • Dinutuximab
    • Edoxaban
    • Empagliflozin/Linagliptin
    • Ferric pyrophosphate citrate
    • Finafloxacin
    • Isavuconazonium
    • Lamivudine/Raltegravir
    • Lenvatinib
    • Memantine/Donepezil
    • Nintedanib
    • Ombitasvir/Paritaprevir/Ritonavir/Dasabuvir
    • Palbociclib
    • Panobinostat
    • Parathyroid hormone
    • Peramivir
    • Perindopril/Amlodipine
    • Secukinumab
  • New indications/dosing forms for:
    • Aripiprazole
    • Gadobutrol
    • Glatiramer
    • Rifaximin
    • Technetium Tc 99m tilmanocept
  • Dosing updates and changes:
    • Abacavir
    • Abiraterone
    • Bevacizumab
    • Darunavir
    • Emtricitabine/Rilpivirine/Tenofovir
    • Ezogabine
    • Fingolimod
    • Haloperidol
    • Paliperidone
    • Topotecan
Drug Interactions Generator:

Interactions for new and existing drugs added

Medical Calculators:

Emergency Heart Failure Mortality Risk Grade (EHMRG) Calculator


 

PEPID Portable Drug Companion

Special Update:

The U.S. Food and Drug Administration's (FDA) final rule regarding labeling requirements for pregnancy and lactation went into effect on June 30, 2015. As a result, the following changes now apply to PEPID's drug content:

  • “Pregnancy Categories” will be phased out of the content.
  • A new section titled “Pregnancy and Lactation” will contain pertinent data regarding pregnancy, lactation and reproductive risk that will fall in line with the new labeling requirements.
  • New products approved after June 30, 2015, will show this change immediately, as well as products recently approved that are conforming to this change preemptively.
  • Pre-existing products will be updated as the data becomes available.

For more information, visit the FDA website.

Drug Knowledgebase
  • 22 drugs added:
    • Atazanavir/Cobicistat
    • Ceftazidime/Avibactam
    • Cholic Acid
    • Darunavir/Cobicistat
    • Diclofenac IV
    • Dinutuximab
    • Edoxaban
    • Empagliflozin/Linagliptin
    • Ferric pyrophosphate citrate
    • Finafloxacin
    • Isavuconazonium
    • Lamivudine/Raltegravir
    • Lenvatinib
    • Memantine/Donepezil
    • Nintedanib
    • Ombitasvir/Paritaprevir/Ritonavir/Dasabuvir
    • Palbociclib
    • Panobinostat
    • Parathyroid hormone
    • Peramivir
    • Perindopril/Amlodipine
    • Secukinumab
  • New indications/dosing forms for:
    • Aripiprazole
    • Gadobutrol
    • Glatiramer
    • Rifaximin
    • Technetium Tc 99m tilmanocept
  • Dosing updates and changes for:
    • Abacavir
    • Abiraterone
    • Bevacizumab
    • Darunavir
    • Emtricitabine/Rilpivirine/Tenofovir
    • Ezogabine
    • Fingolimod
    • Haloperidol
    • Paliperidone
    • Topotecan
Drug Interactions Generator:

Interactions for new and existing drugs added

New or Updated Evidence-based Medicine:
  • Evidence-based Inquiries
  • Clinical Inquiries
  • PURLs

 

AHFS Drug Information® by PEPID

Drugs
  • New monographs:
    • Mechlorethamine (Topical)
    • Ramucirumab
    • Dalbavancin
    • Oritavancin
    • Tedizolid
    • Eslicarbazepine
    • Ferric Carboxymaltose
    • AbobotulinumtoxinA
    • IncobotulinumtoxinA
    • RimabotulinumtoxinB
    • Botulism Antitoxin (Equine)
    • Vedolizumab
    • Pembrolizumab
    • Idelalisib
    • Ledipasvir/Sofosbuvir
    • Dulaglutide
    • Nivolumab
    • Droxidopa
    • Secukinumab
    • Ombitasvir, Paritaprevir and Ritonavir with Dasabuvir Sodium
  • Revised monographs:
    • Mifepristone
    • Teriparatide
    • Ferumoxytol
    • Simeprevir
    • Sofosbuvir
    • Clorazepate
    • Mechlorethamine
    • Tocilizumab
    • Vemurafenib
    • Glycopyrrolate
    • Verapamil
  • Revised monographs, cont.:
    • Cisplatin
    • Flecainide
    • Ciprofloxacin
    • Propafenone
    • Paclitaxel
    • Amiodarone
    • Olanzapine
    • Oseltamivir
    • Cetuximab
    • OnabotulinumtoxinA
    • Sunitinib
    • Fosinopril
    • Moexipril
    • Milnacipran
    • Canagliflozin
    • Levomilnacipran
    • Dapagliflozin
    • Pneumococcal Vaccine
    • Infliximab
    • Mycophenolate
    • Adenosine
    • Antithrombin alfa
    • Regadenoson
    • Rivaroxaban
    • Ezogabine
    • Hydrocodone
    • Aminocaproic Acid
    • Protamine
    • Heparin
    • Japanese Encephalitis Vaccine
    • Docetaxel
Drug Interactions Generator:

Interactions for new and existing drugs added

Medical Calculators:

Emergency Heart Failure Mortality Risk Grade (EHMRG) Calculator


 

AHFS Drug Information Essentials® by PEPID

Drugs
  • New monographs:
    • Mechlorethamine (Topical)
    • Ramucirumab
    • Dalbavancin
    • Oritavancin
    • Tedizolid
    • Eslicarbazepine
    • Ferric Carboxymaltose
    • AbobotulinumtoxinA
    • IncobotulinumtoxinA
    • RimabotulinumtoxinB
    • Botulism Antitoxin (Equine)
    • Vedolizumab
    • Pembrolizumab
    • Idelalisib
    • Ledipasvir/Sofosbuvir
    • Dulaglutide
    • Nivolumab
  • Revised monographs:
    • Mifepristone
    • Teriparatide
    • Ferumoxytol
    • Simeprevir
    • Sofosbuvir
    • Clorazepate
  • Revised monographs, cont.:
    • Amiodarone
    • Olanzapine
    • Oseltamivir
    • Cetuximab
    • OnabotulinumtoxinA
    • Sunitinib
    • Milnacipran
    • Canagliflozin
    • Levomilnacipran
    • Dapagliflozin
    • Pneumococcal Vaccine
    • Infliximab
    • Lepirudin
    • Mycophenolate
    • Adenosine
    • Protein C Concentrate
    • Antithrombin alfa
    • Regadenoson
    • Ezogabine
    • Hydrocodone
    • Protamine
    • Alteplase
    • Japanese Encephalitis Vaccine
    • Docetaxel
Drug Interactions Generator:

Interactions for new and existing drugs added

Medical Calculators:

Emergency Heart Failure Mortality Risk Grade (EHMRG) Calculator


 

PEPID Pharmacist Pro with AHFS

Special Updates:

  • Powdered Alcohol (Palcohol)

    In March 2015, the Alcohol and Tobacco Tax and Trade Bureau (TTB) had approved for sale and distribution in the USA of several powdered alcohol products. Powdered alcohol is ethanol (drinking alcohol) which has been absorbed into a carbohydrate medium (e.g., dextrin) in order to maintain a dry powder or crystalline form. As of August 2015, 22 states have banned powdered alcohol, 20 states statutorily prohibit the sale of powdered alcohol, two states have temporary one-year statutory bans, and four states regulate it under their existing alcohol statutes.

  • Pregnancy Categories

    The U.S. Food and Drug Administration's (FDA) final rule regarding labeling requirements for pregnancy and lactation became effective on June 30, 2015. As a result, the following changes will apply to PEPID Drug content:

    • “Pregnancy Categories” will be phased out of the content.
    • A new section titled “Pregnancy and Lactation” will contain pertinent data regarding pregnancy, lactation and reproductive risk that will fall in line with the new labeling requirements.
    • New products approved will show this change immediately, as well as products recently approved that are conforming to this change preemptively.
    • Pre-existing products will be updated as the data becomes available.

For more information, visit the FDA website.

Medical Content
  • Allergy & Immunology
    • Angioedema — ACEi Induced
  • Cardiology
    • Cardiorenal Syndrome
    • Commotio Cordis
  • Gastroenterology
    • Chronic Pancreatitis
    • Diverticulosis
  • Geriatrics
    • Inappropriate Drug Use in Geriatrics
  • Hematology and Oncology
    • Disseminated Intravascular Coagulation
  • Infectious Disease
    • Condyloma Acuminatum
    • Helicobacter Pylori
  • Metabolic Disorders
    • Respiratory Acidosis
  • Neurology
    • Acoustic Neuroma
  • Obstetrics and Gynecology
    • Appendicitis in Pregnancy
    • Eclampsia
    • Pelvic and Lower Back Pain in Pregnancy
    • Postpartum Hemorrhage
  • Ophthalmology
    • Glaucoma
  • Orthopedics
    • Elbow Dislocation
  • Prevention
    • Healthy Adult Exam
  • Psychiatry
    • Autism Spectrum Disorder (Adult)
    • Narcissistic Personality Disorder
    • Substance Abuse in Adolescents
  • Sports Medicine
    • Iliac Artery Endofibrosis
  • Toxicology
    • Sympathomimetics/CNS Stimulants
    • Methanol Poisoning
  • Transplant Management
    • Overview
    • Post-Transplantation: Infection Differential
  • Trauma
    • Advance Trauma Life Support (ATLS)
    • Trauma Basics (ABCDEs): Resuscitation Overview
    • Primary Survey
      • Overview
      • Airway and C-Spine
      • Breathing
      • Circulation
      • Control Bleeding
      • Disability
      • Exposure and Environment
    • Secondary Survey
      • Overview
      • Head and Neck
      • Chest
      • Abdomen and Pelvis
      • Extremities
    • Burns
      • Overview
      • Treatment of Minor to Moderate Burns
      • Treatment of Major Burns
      • Inhalation Injury
    • Urology
      • Urinary Tract Infection (Pediatric)
Evidence-based Medicine
  • 11 clinical inquiries added:
    • What is the best beta-blocker for systolic heart failure?
    • Does topical diclofenac relieve osteoarthritis pain?
    • Does frenotomy help infants with tongue-tie overcome breastfeeding difficulties?
    • Is red-yeast rice a safe and effective alternative to statins?
    • Does the presence of a trained support person during labor decrease C-section rates?
    • How well do antivirals shorten genital herpes pain duration?
    • Are inhaled steroids effective for a postviral cough?
    • Does primary nocturnal enuresis affect children's self-esteem?
    • What therapies alleviate symptoms of polycystic ovary syndrome?
    • Do statins increase the risk of developing diabetes?
    • What's the best test for underlying osteomyelitis in patients with diabetic foot ulcers?
  • 4 PURLs added:
    • Skip this step when checking lipid levels
    • A new adjunctive Tx option for venous stasis ulcers
    • Consider these medications to help patients stay sober
    • Another good reason to recommend low-dose aspirin
  • 54 evidence-based practice journal entries added:
    • Should patients with elevated CRP levels and no other risk factors be started on a statin?
    • Are diuretics effective for idiopathic lymphedema?
    • For pregnant patients who smoke, is nicotine replacement therapy more effective than counseling or no intervention for achieving successful smoking cessation?
    • What causes delayed gastric emptying (gastroparesis) besides diabetes?
    • Are leukotriene receptor antagonists beneficial for the management of adults with asthma exacerbations?
    • How effective are lower extremity compression devices for reducing DVT risk after a stroke?
    • Is modafinil safe and effective at improving mental performance in shift workers?
    • How should a positive urine urobilinogen dipstick test be evaluated?
    • Does reduction or modification of dietary fat intake decrease rates of myocardial infarction, stroke, or death in patients?
    • Besides HCTZ, do other diuretics increase the risk of gout?
    • Optimal route of misoprostol administration for the prevention of postpartum hemorrhage
    • Are SSRIs effective in reducing pain in patients with chronic pain?
    • Do you need to follow hCG (human chorionic gonadotropin) levels to zero for everyone who has had a spontaneous abortion?
    • Does the use of supplemental garlic decrease blood pressure in hypertensive patients?
    • What is the impact of blood cultures on community-acquired pneumonia?
    • What is the best treatment for an adult with an umbilical hernia?
    • Does the combination of simvastatin with amlodipine increase the risk of myopathy?
    • In a perimenopausal woman, what is the best way to diagnose menopause?
    • Are there any risks to taking creatine as a supplement?
    • Does exercise improve postpartum depression symptoms?
    • What is the best pharmaceutical to treat anxiety among institutionalized elderly?
    • Are custom orthotics significantly more effective in reducing plantar pressure in patients with diabetes?
    • Does breastfeeding lead to more postpartum weight loss compared with non-breastfeeding?
    • What effect does exercise have on the immune system?
    • What is the best treatment for ankylosing spondylitis?
    • What is the safest treatment for constipation in children?
    • What nonpharmacologic interventions are effective for reducing needle-related procedural pain in children and adolescents?
    • Does depression and anxiety lead to overeating in children?
    • What is the effect of oral vinegar ingestion on postprandial glucose levels?
    • How accurate are blood glucose meters?
    • Does counseling on or the distribution of devices for the safe storage of firearms increase their safe storage among firearm owners with children?
    • When should MRSA eradication be attempted for patient with colonization or infection?
    • Does recreational running increase the risk of OA of the knee?
    • Are dietary interventions effective in the treatment of multiple sclerosis?
    • What is the best treatment for low HDL?
    • What is the most effective therapy for childhood attention deficit hyperactivity disorder (ADHD)?
    • Is it okay to use the nicotine patch during pregnancy?
    • Which opioid is best for the management of labor pain?
    • What nonpharmacologic therapies for patients with chronic vertigo, not from Meniere’s disease, are effective for the relief of symptoms?
    • BID vs TID dosing of unfractionated heparin for venous thromboembolism (VTE) prophylaxis in hospitalized patients
    • Should we screen for osteoporosis using calcaneal ultrasound?
    • Does cranberry juice or cranberry extract reduce the frequency of recurrent urinary tract infections in women?
    • Are there any long-term detrimental effects from soy formula?
    • Is there any benefit to continuing cervical Pap smears for women older than 65 with a history of normal Pap results?
    • In adult patients with chronic sinusitis, what are the indications for specialist referral?
    • Is spinal manipulation therapy more effective than home exercise as a treatment for neck pain?
    • Does coenzyme Q10 supplementation help reduce statin-induced myalgia?
    • How long should a patient wait before attempting pregnancy again after a spontaneous abortion?
    • Is screening colonoscopy more effective than annual FOBT in improving morbidity and mortality for colon cancer screening in adults?
    • Can metformin be used safely in a patient with elevated creatinine concentration?
    • Does supplementation with zinc magnesium aspartate (ZMA) increase levels of serum testosterone in men?
    • Do probiotics decrease the incidence and symptoms of recurrent vaginal yeast infections?
    • Are computer-based interventions effective for decreasing symptoms in adolescents with major depression?
    • What is the best treatment for medication-induced rebound headaches?
  • 2 U.S. Preventive Services Task Force Recommendations added:
    • Thyroid Dysfunction: Screening
    • Speech and Language Delay and Disorders in Children Age 5 and Younger: Screening
Drug Knowledgebase
  • New monographs:
    • Mechlorethamine (Topical)
    • Ramucirumab
    • Dalbavancin
    • Oritavancin
    • Tedizolid
    • Eslicarbazepine
    • Ferric Carboxymaltose
    • AbobotulinumtoxinA
    • IncobotulinumtoxinA
    • RimabotulinumtoxinB
    • Botulism Antitoxin (Equine)
    • Vedolizumab
    • Pembrolizumab
    • Idelalisib
    • Ledipasvir/Sofosbuvir
    • Dulaglutide
    • Nivolumab
  • Revised monographs:
    • Mifepristone
    • Teriparatide
    • Ferumoxytol
    • Simeprevir
    • Sofosbuvir
    • Clorazepate
  • Revised monographs, cont.:
    • Amiodarone
    • Olanzapine
    • Oseltamivir
    • Cetuximab
    • OnabotulinumtoxinA
    • Sunitinib
    • Milnacipran
    • Canagliflozin
    • Levomilnacipran
    • Dapagliflozin
    • Pneumococcal Vaccine
    • Infliximab
    • Lepirudin
    • Mycophenolate
    • Adenosine
    • Protein C Concentrate
    • Antithrombin alfa
    • Regadenoson
    • Ezogabine
    • Hydrocodone
    • Protamine
    • Alteplase
    • Japanese Encephalitis Vaccine
    • Docetaxel
Drug Interactions Generator:

Interactions for new and existing drugs added

Medical Calculators:

Emergency Heart Failure Mortality Risk Grade (EHMRG) Calculator


 

PEPID Nursing Suites

Professional Nursing, Student Nursing, Oncology Nursing, Gerontological Nursing and Critical Care Nursing


Special Updates:

  • Powdered Alcohol (Palcohol)

    In March 2015, the Alcohol and Tobacco Tax and Trade Bureau (TTB) had approved for sale and distribution in the USA of several powdered alcohol products. Powdered alcohol is ethanol (drinking alcohol) which has been absorbed into a carbohydrate medium (e.g., dextrin) in order to maintain a dry powder or crystalline form. As of August 2015, 22 states have banned powdered alcohol, 20 states statutorily prohibit the sale of powdered alcohol, two states have temporary one-year statutory bans, and four states regulate it under their existing alcohol statutes.

  • Pregnancy Categories

    The U.S. Food and Drug Administration's (FDA) final rule regarding labeling requirements for pregnancy and lactation became effective on June 30, 2015. As a result, the following changes will apply to PEPID Drug content:

    • “Pregnancy Categories” will be phased out of the content.
    • A new section titled “Pregnancy and Lactation” will contain pertinent data regarding pregnancy, lactation and reproductive risk that will fall in line with the new labeling requirements.
    • New products approved will show this change immediately, as well as products recently approved that are conforming to this change preemptively.
    • Pre-existing products will be updated as the data becomes available.

For more information, visit the FDA website.

Medical/Nursing Content
  • New and updated medical monographs:
    • Allergy & Immunology
      • Angioedema — ACEi Induced
    • Cardio/Vascular
      • Cardiorenal Syndrome
      • Commotio Cordis
      • Endofibrosis of Iliac Artery
      • Joint National Committee (JNC) 8
    • FDEENT
      • Acoustic Neuroma
      • Glaucoma
    • Gastroenterology
      • Chronic Pancreatitis
      • Diverticulosis
    • Geriatrics
      • Falls in the Elderly
      • Get Up & Go Test
      • Inappropriate Drug Use
    • Hematology/Oncology
      • Disseminated Intravascular Coagulation (DIC)
    • Infectious Disease
      • Condyloma Acuminata
      • Helicobacter Pylori
      • West Nile Virus
    • Metabolic/Endocrine
      • Respiratory Acidosis
    • Obstetrics/Gynecology
      • Appendicitis in Pregnancy
      • Eclampsia
      • Pelvic and Lower Back Pain in Pregnancy
      • Postpartum Hemorrhage
    • Orthopedics
      • Elbow Dislocation
    • Pediatrics
      • Substance Abuse: Children/Adolescents, Overview and Statistics
        • Substance Abuse in Adolescents
      • Urinary Tract Infection
    • Procedures
      • Mechanical Ventilation
        • Ventilator Management: Overview
        • Ventilator Management: Settings
        • Ventilator Management: Manipulations
        • Ventilator Management: Troubleshooting
    • Psychiatry/Addiction
      • Autism Spectrum Disorder (Adult)
      • Narcissistic Personality Disorder
      • Substance Abuse: Children/Adolescents, Overview and Statistics
        • Substance Abuse in Adolescents
    • Respiratory
      • Respiratory Acidosis
    • Sports Medicine
      • Endofibrosis of Iliac Artery
    • Toxicology
      • Ethanol (EtOH) Toxicity
      • Powdered Alcohol (Palcohol)
      • Sympathomimetics/CNS Stimulants
      • Methanol Poisoning
    • Transplant Management
      • Overview
      • Post-Transplantation: Infection Differential
    • Trauma
      • Advance Trauma Life Support (ATLS)
        • Trauma Basics (ABCDEs): Resuscitation Overview
        • Trauma Basics (ABCDEs): General Principles
      • Primary Survey
        • Overview
        • Airway and C-Spine
        • Breathing
        • Circulation
        • Control Bleeding
        • Disability/Neurological Status
        • Exposure and Environment
      • Secondary Survey
        • Overview
        • Head and Neck
        • Chest
        • Abdomen and Pelvis
        • Extremities
      • Commotion Cordis
  • New and updated Nursing Considerations in medical monographs:
    • Acoustic Neuroma
    • Aseptic Meningitis (Peds)
    • Autism Spectrum Disorder (Adult)
    • Bacterial Meningitis (Peds)
    • Bipolar Disorder
    • Celiac Disease
    • Falls In The Elderly
    • Idiopathic Pulmonary Fibrosis
    • Irritable Bowel Syndrome
    • Lung Cancer
    • Overactive Bladder
    • Pancreatic Cancer
    • Postpartum Hemorrhage
    • Prostate Cancer
    • Pulmonary Hypertension
    • Schizophrenia
    • Transient Synovitis of the Hip
    • Upper Respiratory Tract Infection
    • Viral Meningitis (Peds)
  • New, expanded or updated Nursing Considerations in drug monographs:
    • Dicyclomine
    • Glycopyrrolate
    • Hyoscyamine
    • Hyoscyamine Spray
    • Mepenzolate
    • Methscopolamine
    • Sucralfate
    • Magnesium Citrate
    • Magnesium Hydroxide
    • Sodium Phosphate
    • Bisacodyl
    • Cascara Sagrada
    • Castor Oil
    • Senna
    • Malt Soup Extract
    • Methylcellulose
    • Polycarbophil
    • Psyllium
    • Sterculia
    • Mineral Oil
    • Docusate Sodium
    • Polyethylene Glycol
    • Sodium Sulfate, Potassium Sulfate, Magnesium Sulfate
    • Casanthranol/Docusate Sodium
    • Magnesium Hydroxide/ Mineral Oil
    • MoviPrep
    • Prepopik
    • Enemas
  • New or updated evidence-based practice:
    • Evidence-Based Practice Inquiries
    • Clinical Inquiries
    • PURLs
    • U.S. Preventive Services Task Force Recommendations
Drug Knowledgebase
  • 22 drugs added:
    • Atazanavir/Cobicistat
    • Ceftazidime/Avibactam
    • Cholic Acid
    • Darunavir/Cobicistat
    • Diclofenac IV
    • Dinutuximab
    • Edoxaban
    • Empagliflozin/Linagliptin
    • Ferric pyrophosphate citrate
    • Finafloxacin
    • Isavuconazonium
    • Lamivudine/Raltegravir
    • Lenvatinib
    • Memantine/Donepezil
    • Nintedanib
    • Ombitasvir/Paritaprevir/Ritonavir/Dasabuvir
    • Palbociclib
    • Panobinostat
    • Parathyroid hormone
    • Peramivir
    • Perindopril/Amlodipine
    • Secukinumab
  • New indications/dosing forms for:
    • Aripiprazole
    • Gadobutrol
    • Glatiramer
    • Rifaximin
    • Technetium Tc 99m tilmanocept
  • Dosing updates and changes:
    • Abacavir
    • Abiraterone
    • Bevacizumab
    • Darunavir
    • Emtricitabine/Rilpivirine/Tenofovir
    • Ezogabine
    • Fingolimod
    • Haloperidol
    • Paliperidone
    • Topotecan
Drug Interactions Generator:

Interactions for new and existing drugs added

Medical Calculators:

Emergency Heart Failure Mortality Risk Grade (EHMRG) Calculator


 

PEPID Primary Care Plus Ambulatory Care Suite

Special Updates:

  • Powdered Alcohol (Palcohol)

    In March 2015, the Alcohol and Tobacco Tax and Trade Bureau (TTB) had approved for sale and distribution in the USA of several powdered alcohol products. Powdered alcohol is ethanol (drinking alcohol) which has been absorbed into a carbohydrate medium (e.g., dextrin) in order to maintain a dry powder or crystalline form. As of August 2015, 22 states have banned powdered alcohol, 20 states statutorily prohibit the sale of powdered alcohol, two states have temporary one-year statutory bans, and four states regulate it under their existing alcohol statutes.

  • Pregnancy Categories

    The U.S. Food and Drug Administration's (FDA) final rule regarding labeling requirements for pregnancy and lactation became effective on June 30, 2015. As a result, the following changes will apply to PEPID Drug content:

    • “Pregnancy Categories” will be phased out of the content.
    • A new section titled “Pregnancy and Lactation” will contain pertinent data regarding pregnancy, lactation and reproductive risk that will fall in line with the new labeling requirements.
    • New products approved will show this change immediately, as well as products recently approved that are conforming to this change preemptively.
    • Pre-existing products will be updated as the data becomes available.

For more information, visit the FDA website.

Medical Content
  • Allergy & Immunology
    • Angioedema — ACEi Induced
  • Cardiology
    • Cardiorenal Syndrome
    • Commotio Cordis
  • Gastroenterology
    • Chronic Pancreatitis
    • Diverticulosis
  • Geriatrics
    • Inappropriate Drug Use in Geriatrics
  • Hematology and Oncology
    • Disseminated Intravascular Coagulation
  • Infectious Disease
    • Condyloma Acuminatum
    • Helicobacter Pylori
    • West Nile Virus
  • Metabolic Disorders
    • Respiratory Acidosis
  • Neurology
    • Acoustic Neuroma
  • Obstetrics and Gynecology
    • Appendicitis in Pregnancy
    • Eclampsia
    • Pelvic and Lower Back Pain in Pregnancy
    • Postpartum Hemorrhage
  • Ophthalmology
    • Glaucoma
  • Orthopedics
    • Elbow Dislocation
  • Prevention
    • Healthy Adult Exam
  • Psychiatry
    • Autism Spectrum Disorder (Adult)
    • Narcissistic Personality Disorder
    • Substance Abuse in Adolescents
  • Sports Medicine
    • Iliac Artery Endofibrosis
  • Toxicology
    • Ethanol (EtOH) Toxicity
    • Sympathomimetics/CNS Stimulants
    • Methanol Poisoning
  • Transplant Management
    • Overview
    • Post-Transplantation: Infection Differential
  • Trauma
    • Advance Trauma Life Support (ATLS)
    • Trauma Basics (ABCDEs): Resuscitation Overview
    • Primary Survey
      • Overview
      • Airway and C-Spine
      • Breathing
      • Circulation
      • Control Bleeding
      • Disability
      • Exposure and Environment
    • Secondary Survey
      • Overview
      • Head and Neck
      • Chest
      • Abdomen and Pelvis
      • Extremities
    • Burns
      • Overview
      • Treatment of Minor to Moderate Burns
      • Treatment of Major Burns
      • Inhalation Injury
    • Urology
      • Urinary Tract Infection (Pediatric)
Evidence-based Medicine
  • 11 clinical inquiries added:
    • What is the best beta-blocker for systolic heart failure?
    • Does topical diclofenac relieve osteoarthritis pain?
    • Does frenotomy help infants with tongue-tie overcome breastfeeding difficulties?
    • Is red-yeast rice a safe and effective alternative to statins?
    • Does the presence of a trained support person during labor decrease C-section rates?
    • How well do antivirals shorten genital herpes pain duration?
    • Are inhaled steroids effective for a postviral cough?
    • Does primary nocturnal enuresis affect children's self-esteem?
    • What therapies alleviate symptoms of polycystic ovary syndrome?
    • Do statins increase the risk of developing diabetes?
    • What's the best test for underlying osteomyelitis in patients with diabetic foot ulcers?
  • 4 PURLs added:
    • Skip this step when checking lipid levels
    • A new adjunctive Tx option for venous stasis ulcers
    • Consider these medications to help patients stay sober
    • Another good reason to recommend low-dose aspirin
  • 54 evidence-based practice journal entries added:
    • Should patients with elevated CRP levels and no other risk factors be started on a statin?
    • Are diuretics effective for idiopathic lymphedema?
    • For pregnant patients who smoke, is nicotine replacement therapy more effective than counseling or no intervention for achieving successful smoking cessation?
    • What causes delayed gastric emptying (gastroparesis) besides diabetes?
    • Are leukotriene receptor antagonists beneficial for the management of adults with asthma exacerbations?
    • How effective are lower extremity compression devices for reducing DVT risk after a stroke?
    • Is modafinil safe and effective at improving mental performance in shift workers?
    • How should a positive urine urobilinogen dipstick test be evaluated?
    • Does reduction or modification of dietary fat intake decrease rates of myocardial infarction, stroke, or death in patients?
    • Besides HCTZ, do other diuretics increase the risk of gout?
    • Optimal route of misoprostol administration for the prevention of postpartum hemorrhage
    • Are SSRIs effective in reducing pain in patients with chronic pain?
    • Do you need to follow hCG (human chorionic gonadotropin) levels to zero for everyone who has had a spontaneous abortion?
    • Does the use of supplemental garlic decrease blood pressure in hypertensive patients?
    • What is the impact of blood cultures on community-acquired pneumonia?
    • What is the best treatment for an adult with an umbilical hernia?
    • Does the combination of simvastatin with amlodipine increase the risk of myopathy?
    • In a perimenopausal woman, what is the best way to diagnose menopause?
    • Are there any risks to taking creatine as a supplement?
    • Does exercise improve postpartum depression symptoms?
    • What is the best pharmaceutical to treat anxiety among institutionalized elderly?
    • Are custom orthotics significantly more effective in reducing plantar pressure in patients with diabetes?
    • Does breastfeeding lead to more postpartum weight loss compared with non-breastfeeding?
    • What effect does exercise have on the immune system?
    • What is the best treatment for ankylosing spondylitis?
    • What is the safest treatment for constipation in children?
    • What nonpharmacologic interventions are effective for reducing needle-related procedural pain in children and adolescents?
    • Does depression and anxiety lead to overeating in children?
    • What is the effect of oral vinegar ingestion on postprandial glucose levels?
    • How accurate are blood glucose meters?
    • Does counseling on or the distribution of devices for the safe storage of firearms increase their safe storage among firearm owners with children?
    • When should MRSA eradication be attempted for patient with colonization or infection?
    • Does recreational running increase the risk of OA of the knee?
    • Are dietary interventions effective in the treatment of multiple sclerosis?
    • What is the best treatment for low HDL?
    • What is the most effective therapy for childhood attention deficit hyperactivity disorder (ADHD)?
    • Is it okay to use the nicotine patch during pregnancy?
    • Which opioid is best for the management of labor pain?
    • What nonpharmacologic therapies for patients with chronic vertigo, not from Meniere’s disease, are effective for the relief of symptoms?
    • BID vs TID dosing of unfractionated heparin for venous thromboembolism (VTE) prophylaxis in hospitalized patients
    • Should we screen for osteoporosis using calcaneal ultrasound?
    • Does cranberry juice or cranberry extract reduce the frequency of recurrent urinary tract infections in women?
    • Are there any long-term detrimental effects from soy formula?
    • Is there any benefit to continuing cervical Pap smears for women older than 65 with a history of normal Pap results?
    • In adult patients with chronic sinusitis, what are the indications for specialist referral?
    • Is spinal manipulation therapy more effective than home exercise as a treatment for neck pain?
    • Does coenzyme Q10 supplementation help reduce statin-induced myalgia?
    • How long should a patient wait before attempting pregnancy again after a spontaneous abortion?
    • Is screening colonoscopy more effective than annual FOBT in improving morbidity and mortality for colon cancer screening in adults?
    • Can metformin be used safely in a patient with elevated creatinine concentration?
    • Does supplementation with zinc magnesium aspartate (ZMA) increase levels of serum testosterone in men?
    • Do probiotics decrease the incidence and symptoms of recurrent vaginal yeast infections?
    • Are computer-based interventions effective for decreasing symptoms in adolescents with major depression?
    • What is the best treatment for medication-induced rebound headaches?
  • 2 U.S. Preventive Services Task Force Recommendations added:
    • Thyroid Dysfunction: Screening
    • Speech and Language Delay and Disorders in Children Age 5 and Younger: Screening
Drug Knowledgebase
  • 22 drugs added:
    • Atazanavir/Cobicistat
    • Ceftazidime/Avibactam
    • Cholic Acid
    • Darunavir/Cobicistat
    • Diclofenac IV
    • Dinutuximab
    • Edoxaban
    • Empagliflozin/Linagliptin
    • Ferric pyrophosphate citrate
    • Finafloxacin
    • Isavuconazonium
    • Lamivudine/Raltegravir
    • Lenvatinib
    • Memantine/Donepezil
    • Nintedanib
    • Ombitasvir/Paritaprevir/Ritonavir/Dasabuvir
    • Palbociclib
    • Panobinostat
    • Parathyroid hormone
    • Peramivir
    • Perindopril/Amlodipine
    • Secukinumab
  • New indications/dosing forms for:
    • Aripiprazole
    • Gadobutrol
    • Glatiramer
    • Rifaximin
    • Technetium Tc 99m tilmanocept
  • Dosing updates and changes:
    • Abacavir
    • Abiraterone
    • Bevacizumab
    • Darunavir
    • Emtricitabine/Rilpivirine/Tenofovir
    • Ezogabine
    • Fingolimod
    • Haloperidol
    • Paliperidone
    • Topotecan
Drug Interactions Generator:

Interactions for new and existing drugs added

Medical Calculators:

Emergency Heart Failure Mortality Risk Grade (EHMRG) Calculator


 

PEPID Clinical Rotation Companion Suite

Special Updates:

  • Powdered Alcohol (Palcohol)

    In March 2015, the Alcohol and Tobacco Tax and Trade Bureau (TTB) had approved for sale and distribution in the USA of several powdered alcohol products. Powdered alcohol is ethanol (drinking alcohol) which has been absorbed into a carbohydrate medium (e.g., dextrin) in order to maintain a dry powder or crystalline form. As of August 2015, 22 states have banned powdered alcohol, 20 states statutorily prohibit the sale of powdered alcohol, two states have temporary one-year statutory bans, and four states regulate it under their existing alcohol statutes.

  • Pregnancy Categories

    The U.S. Food and Drug Administration's (FDA) final rule regarding labeling requirements for pregnancy and lactation became effective on June 30, 2015. As a result, the following changes will apply to PEPID Drug content:

    • “Pregnancy Categories” will be phased out of the content.
    • A new section titled “Pregnancy and Lactation” will contain pertinent data regarding pregnancy, lactation and reproductive risk that will fall in line with the new labeling requirements.
    • New products approved will show this change immediately, as well as products recently approved that are conforming to this change preemptively.
    • Pre-existing products will be updated as the data becomes available.

For more information, visit the FDA website.

Medical Content
  • Allergy & Immunology
    • Angioedema — ACEi Induced
  • Cardiology
    • Cardiorenal Syndrome
    • Commotio Cordis
  • Gastroenterology
    • Chronic Pancreatitis
    • Diverticulosis
  • Geriatrics
    • Inappropriate Drug Use in Geriatrics
  • Hematology and Oncology
    • Disseminated Intravascular Coagulation
  • Infectious Disease
    • Condyloma Acuminatum
    • Helicobacter Pylori
    • West Nile Virus
  • Metabolic Disorders
    • Respiratory Acidosis
  • Neurology
    • Acoustic Neuroma
  • Obstetrics and Gynecology
    • Appendicitis in Pregnancy
    • Eclampsia
    • Pelvic and Lower Back Pain in Pregnancy
    • Postpartum Hemorrhage
  • Ophthalmology
    • Glaucoma
  • Orthopedics
    • Elbow Dislocation
  • Prevention
    • Healthy Adult Exam
  • Psychiatry
    • Autism Spectrum Disorder (Adult)
    • Narcissistic Personality Disorder
    • Substance Abuse in Adolescents
  • Sports Medicine
    • Iliac Artery Endofibrosis
  • Toxicology
    • Ethanol (EtOH) Toxicity
    • Sympathomimetics/CNS Stimulants
    • Methanol Poisoning
  • Transplant Management
    • Overview
    • Post-Transplantation: Infection Differential
  • Trauma
    • Advance Trauma Life Support (ATLS)
    • Trauma Basics (ABCDEs): Resuscitation Overview
    • Primary Survey
      • Overview
      • Airway and C-Spine
      • Breathing
      • Circulation
      • Control Bleeding
      • Disability
      • Exposure and Environment
    • Secondary Survey
      • Overview
      • Head and Neck
      • Chest
      • Abdomen and Pelvis
      • Extremities
    • Burns
      • Overview
      • Treatment of Minor to Moderate Burns
      • Treatment of Major Burns
      • Inhalation Injury
    • Urology
      • Urinary Tract Infection (Pediatric)
Evidence-based Medicine
  • 11 clinical inquiries added:
    • What is the best beta-blocker for systolic heart failure?
    • Does topical diclofenac relieve osteoarthritis pain?
    • Does frenotomy help infants with tongue-tie overcome breastfeeding difficulties?
    • Is red-yeast rice a safe and effective alternative to statins?
    • Does the presence of a trained support person during labor decrease C-section rates?
    • How well do antivirals shorten genital herpes pain duration?
    • Are inhaled steroids effective for a postviral cough?
    • Does primary nocturnal enuresis affect children's self-esteem?
    • What therapies alleviate symptoms of polycystic ovary syndrome?
    • Do statins increase the risk of developing diabetes?
    • What's the best test for underlying osteomyelitis in patients with diabetic foot ulcers?
  • 4 PURLs added:
    • Skip this step when checking lipid levels
    • A new adjunctive Tx option for venous stasis ulcers
    • Consider these medications to help patients stay sober
    • Another good reason to recommend low-dose aspirin
  • 54 evidence-based practice journal entries added:
    • Should patients with elevated CRP levels and no other risk factors be started on a statin?
    • Are diuretics effective for idiopathic lymphedema?
    • For pregnant patients who smoke, is nicotine replacement therapy more effective than counseling or no intervention for achieving successful smoking cessation?
    • What causes delayed gastric emptying (gastroparesis) besides diabetes?
    • Are leukotriene receptor antagonists beneficial for the management of adults with asthma exacerbations?
    • How effective are lower extremity compression devices for reducing DVT risk after a stroke?
    • Is modafinil safe and effective at improving mental performance in shift workers?
    • How should a positive urine urobilinogen dipstick test be evaluated?
    • Does reduction or modification of dietary fat intake decrease rates of myocardial infarction, stroke, or death in patients?
    • Besides HCTZ, do other diuretics increase the risk of gout?
    • Optimal route of misoprostol administration for the prevention of postpartum hemorrhage
    • Are SSRIs effective in reducing pain in patients with chronic pain?
    • Do you need to follow hCG (human chorionic gonadotropin) levels to zero for everyone who has had a spontaneous abortion?
    • Does the use of supplemental garlic decrease blood pressure in hypertensive patients?
    • What is the impact of blood cultures on community-acquired pneumonia?
    • What is the best treatment for an adult with an umbilical hernia?
    • Does the combination of simvastatin with amlodipine increase the risk of myopathy?
    • In a perimenopausal woman, what is the best way to diagnose menopause?
    • Are there any risks to taking creatine as a supplement?
    • Does exercise improve postpartum depression symptoms?
    • What is the best pharmaceutical to treat anxiety among institutionalized elderly?
    • Are custom orthotics significantly more effective in reducing plantar pressure in patients with diabetes?
    • Does breastfeeding lead to more postpartum weight loss compared with non-breastfeeding?
    • What effect does exercise have on the immune system?
    • What is the best treatment for ankylosing spondylitis?
    • What is the safest treatment for constipation in children?
    • What nonpharmacologic interventions are effective for reducing needle-related procedural pain in children and adolescents?
    • Does depression and anxiety lead to overeating in children?
    • What is the effect of oral vinegar ingestion on postprandial glucose levels?
    • How accurate are blood glucose meters?
    • Does counseling on or the distribution of devices for the safe storage of firearms increase their safe storage among firearm owners with children?
    • When should MRSA eradication be attempted for patient with colonization or infection?
    • Does recreational running increase the risk of OA of the knee?
    • Are dietary interventions effective in the treatment of multiple sclerosis?
    • What is the best treatment for low HDL?
    • What is the most effective therapy for childhood attention deficit hyperactivity disorder (ADHD)?
    • Is it okay to use the nicotine patch during pregnancy?
    • Which opioid is best for the management of labor pain?
    • What nonpharmacologic therapies for patients with chronic vertigo, not from Meniere’s disease, are effective for the relief of symptoms?
    • BID vs TID dosing of unfractionated heparin for venous thromboembolism (VTE) prophylaxis in hospitalized patients
    • Should we screen for osteoporosis using calcaneal ultrasound?
    • Does cranberry juice or cranberry extract reduce the frequency of recurrent urinary tract infections in women?
    • Are there any long-term detrimental effects from soy formula?
    • Is there any benefit to continuing cervical Pap smears for women older than 65 with a history of normal Pap results?
    • In adult patients with chronic sinusitis, what are the indications for specialist referral?
    • Is spinal manipulation therapy more effective than home exercise as a treatment for neck pain?
    • Does coenzyme Q10 supplementation help reduce statin-induced myalgia?
    • How long should a patient wait before attempting pregnancy again after a spontaneous abortion?
    • Is screening colonoscopy more effective than annual FOBT in improving morbidity and mortality for colon cancer screening in adults?
    • Can metformin be used safely in a patient with elevated creatinine concentration?
    • Does supplementation with zinc magnesium aspartate (ZMA) increase levels of serum testosterone in men?
    • Do probiotics decrease the incidence and symptoms of recurrent vaginal yeast infections?
    • Are computer-based interventions effective for decreasing symptoms in adolescents with major depression?
    • What is the best treatment for medication-induced rebound headaches?
  • 2 U.S. Preventive Services Task Force Recommendations added:
    • Thyroid Dysfunction: Screening
    • Speech and Language Delay and Disorders in Children Age 5 and Younger: Screening
Drug Knowledgebase
  • 22 drugs added:
    • Atazanavir/Cobicistat
    • Ceftazidime/Avibactam
    • Cholic Acid
    • Darunavir/Cobicistat
    • Diclofenac IV
    • Dinutuximab
    • Edoxaban
    • Empagliflozin/Linagliptin
    • Ferric pyrophosphate citrate
    • Finafloxacin
    • Isavuconazonium
    • Lamivudine/Raltegravir
    • Lenvatinib
    • Memantine/Donepezil
    • Nintedanib
    • Ombitasvir/Paritaprevir/Ritonavir/Dasabuvir
    • Palbociclib
    • Panobinostat
    • Parathyroid hormone
    • Peramivir
    • Perindopril/Amlodipine
    • Secukinumab
  • New indications/dosing forms for:
    • Aripiprazole
    • Gadobutrol
    • Glatiramer
    • Rifaximin
    • Technetium Tc 99m tilmanocept
  • Dosing updates and changes:
    • Abacavir
    • Abiraterone
    • Bevacizumab
    • Darunavir
    • Emtricitabine/Rilpivirine/Tenofovir
    • Ezogabine
    • Fingolimod
    • Haloperidol
    • Paliperidone
    • Topotecan
Drug Interactions Generator:

Interactions for new and existing drugs added

Medical Calculators:

Emergency Heart Failure Mortality Risk Grade (EHMRG) Calculator